Niacin, also known as vitamin B3, is a micronutrient with a 40-year history of efficacy in supporting healthy lipid levels, especially high-density lipoprotein cholesterol (HDL-C) levels. However, one side effect often makes supplementing niacin a less than pleasurable experience, limiting adherence. Some patients experience flushing when supplementing niacin. However, a properly- manufactured, sustainedrelease niacin circumvents this side effect. Time Release Niacin is released slowly over a six- to eight-hour period to reduce flushing. T In a double-blind placebo-controlled study, this specific form of Time Release Niacin had only a 5-7 % flush rate, making it well-tolerated and highly effective for supporting balanced cholesterol levels.